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Index > Protein center > Pin1(Gene name) > Mouse
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  • Pin1 (Gene name),
  • Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Protein name ),  PIN1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Pin1;
    Protein name:
    Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1;
    Alternative:
    Peptidyl-prolyl cis-trans isomerase Pin1(PPIase Pin1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with KIF20B (By similarity). Interacts with NEK6 and BTK (By similarity). Interacts with STIL. Interacts (via WW domain) with PRKX.
    Function:
    Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK.
    Subcellular Location:
    Nucleus Co-localizes with NEK6 in the nucleus.
    Protein Attributes:
    Sequence length:
    165
    Sequence:
    50:
    MADEEKLPPG | WEKRMSRSSG | RVYYFNHITN | ASQWERPSGG | STVGGSSKNG | 
    100:
    QGEPAKVRCS | HLLVKHSQSR | RPSSWRQEKI | TRSKEEALEL | INGYIQKIKS | 
    150:
    GEEDFESLAS | QFSDCSSAKA | RGDLGPFSRG | QMQKPFEDAS | FALRTGEMSG | 
    165:
    PVFTDSGIHI | ILRTE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    E7189m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    E7189h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    E7189b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    U7189h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    U7189b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    U7189m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Polyclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    P7189Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Cat.:
    P7189Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Monoclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Monoclonal Antibody for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Protein for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Protein for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Protein for Mouse Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G0 arrest."
      Fujimori F. , Takahashi K. , Uchida C. , Uchida T.
      Biochem. Biophys. Res. Commun.265:658-663(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone marrow.
      tissue: Embryo.
      tissue: Kidney.
      tissue: Oviduct.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Kidney.
    4. 4.
      "Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint."
      Campaner S. , Kaldis P. , Izraeli S. , Kirsch I.R.
      Mol. Cell. Biol.25:6660-6672(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STIL
    5. 5.
      "Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells."
      Phan R.T. , Saito M. , Kitagawa Y. , Means A.R. , Dalla-Favera R.
      Nat. Immunol.8:1132-1139(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN BCL6 STABILITY;DISRUPTION PHENOTYPE
    6. 6.
      "Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development."
      Li X. , Hyink D.P. , Radbill B. , Sudol M. , Zhang H. , Zheleznova N.N. , Wilson P.D.
      Kidney Int.76:54-62(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRKX
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